Andrology
Services
KJK Hospital Fertility Research Centre maintains
a dedicated laboratory offering wide range of andrological
tests from routine semen analysis to complex sperm
function tests. lt is our aim to offer the best
range and standard of tests.
Female
factors
The reasons of female infertility may be due to
failure to ovulate, obstruction to fallopian tube,
infections such as pelvic inflammatory disease
due to tuberculosis or sexually transmitted diseases.
There is a high incidence of endometriosis in
Kerala. In a study conducted in Fertility Centre
for past 4 years, endometriosis has been found
to be the cause in 28% of female causes of infertility.
The cause of high incidence of endometriosis
is not clear but it may be due to environmental
pollutants like Dioxin.
Laparoscopic Surgery which is minimally invasive
surgery is the appropriate method of treatment.
This centre is equipped with most modern gadgets
required for key hole surgery. The patient can
be discharged within 24 hours and can try for
conception immediately. The other advantage is
that the time taken to resume normal activities
is less than 2 weeks when compared to 4-6 weeks
rest advised in Laparotomy. The cost of Laparoscopic
Surgery is equal to open method.
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Ovulation
disorders
This accounts for 30% of female factors. During
a four year study period from 1997-2001 it was
1997-2001 it was found that Polycystic ovary was
the leading causative factor for infertility in
37% of cases. These patients are obese and have
irregular menstrual cylces and may be associated
with increased hair growth.
Assistance may be given to achieve pregnancy
by proper medications, measures taken to reduce
weight and monitoring ovulation by Ultrasound
Doppler Study and estimation of hormones. The
highly sophisticated Toshiba Colour Doppler ultrasound
scanner at the center benefits these patients.
The estimation of hormones is by highly sensitive
Elisa method. To optimise the chances for conception
an ovarian stimulation protocol is followed which
aid growth of follicles and bring about ovulation.
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Assisted Conception Intrauterine
insemination
When conception does not occur normally, Intrauterine
Insemination is carried out which involve drugs
for follicular stimulation and ovulation induction.
When ovulation occurs the sperm sample is carefully
washed and is placed high in the uterus. The treatment
is carried out for 4-5 cycles.
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In Vitro
Fertilisation
This procedure consists of recovering eggs from
the ovary, fertilising them with sperm and transferring
the resulting embryos into the uterus. This is
indicated in tubal damage, severe ovulatory problems,
minor sperm problems and unexplained infertility.
Success rate in this case is around 20-25%.
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Intracytoplasmic
injection
A number of patients undergoing IVF fail to achieve
fertilization where the sperm is unable to penetrate
the outer shell of the egg. ICSI is used to help
men with severe sperm impairment. By directly
injecting the sperm into the cytoplasm of the
egg the natural barriers that the sperm encounters
are bypassed. ICSI is indicated when the semen
parameters are suboptimal, previous failed fertilisation
in IVF and unexplained infertility. The success
is around 40%.
The KJK Fertility Centre is the only one of its
kind which offers ICSI procedure in Trivandrum.
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Cryopreservation
(Freezing and storage)
Sperm Cryopresevation
Most of semen samples can be frozen for long periods
and thawed without loss of fertility. The legal
limit in UK is 10 years. Sperm Cryopreservation
is indicated prior to radio/chemotherapy prior
to vasectomy, husbands working in gulf countries
and donor insemination.
Embryo Cryopreservation
Embryo Cryopreservation is indicated depending
on the quality of spare embryos that may be frozen
for transfer at a later date. The replacement
of frozen embryos can be carried out after treatment
with hormone replacement therapy.
This centre has facilities for sperm and embryo
freezing using latest technology of Cryologic
from Australia. The only centre which offers Cryopreservation
in the capital.
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Other
services provided
Laparoscopic Surgery for fibroids of uterus, cysts
in the ovary, microtubal anastomosis for recanalisation.
Gynaec cases- Conservative surgery as well as
Hysterectomy-Conventional and Laparoscopic assisted.
Hysteroscopic procedures for viewing inside the
uterus and surgery like incision of septae, cannulation
of tubes, removal of submucous fibroids and resection
of the endometrium in patients who want to retain
the uterus in severe bleeding (DUB) Interventional
Sonography -with help of ultrasound, operative
procedures are carried out such as foetal reduction,
aspiration of cysts.
FOGSI (Federation of Obstetric and Gynaecologic
societies of India has recognised this Fertility
Centre for training in Laparoscopy.
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